Are we ready to consider lung recruitability during mechanical ventilation of neonates?

Randomised controlled trials in preterm infants comparing HFOV to conventional ventilation have shown inconsistent results, with no overall differences in mortality but a small trend toward lower BPD incidence with HFOV. 1 Importantly, though, the benefit was greatest when HFOV was applied with an effective ‘high-lung volume strategy’, and least when HFOV was not (especially if lung protection was optimised during conventional ventilation). 1 A high-lung volume strategy prioritises achieving recruitment during HFOV.

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