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Human donor islets coated with functionalized chitosan and alginate nanoscale layers can restore normoglycemia in diabetic mice.

Mater Today Bio · 2026 · PMC12813323 · PMID 41560789

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a decreasing trendno p-value reported
Stimulation index showed a decreasing trend for both groups at later time points, especially day 8, likely reflecting the islets’ in vitro lifespan limit as described in section 3.2 . 3.4.

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