Barely Significant
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Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2021: results from the Global Burden of Disease Study 2021.

BMJ Public Health · 2026 · PMC12815125 · PMID 41561564

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a decreasing trendno p-value reported
First, while previous GBD analyses have documented a decreasing trend in age-standardised death rates from COPD, despite increasing absolute numbers due to population growth and ageing from 1990 to 2017, 7 there is a lack of comprehensive analysis examining how COPD’s relative contribution to the total disease burden has evolved over time.

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