A decreasing trend of tumor growth rates in Stt3a -KO cells and Stt3b -KO cells may be explained by a slightly slower cell proliferation than Stt3a -RE and Stt3b -RE cells as judged by cell counting ( Fig. 3C and D ) and 5-bromo-2′-deoxyuridine (BrdU) uptake assay ( Fig. 3E , F , S2A ).
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Functional inactivation of oligosaccharyltransferase a isoform suppresses tumor metastasis.
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