The MAD2L1-FOXM1 axis negatively regulates CD4⁺ T cell and macrophages infiltration in lung adenocarcinoma.

Discov Oncol · 2026 · PMC12824082 · PMID 41533300

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a decreasing trendno p-value reported

Conversely, the negative gene panel consisting of MPEG1, MS4A14, GIMAP8 and IL3RA demonstrated a decreasing trend across advancing stages (Supplementary Fig. 3B).

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highly significantno p-value reported

Only top 10 positively and negatively genes were considered for further analysis based on their strongest correlation coefficients and highly significant p-values.

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