An increasing trend was observed with 4HNE in dopaminergic cells containing α-syn, compared to cells from age-matched controls; however, this was not significant, while there was a significant increase in 4HNE in cells without α-syn, compared to cells from age-matched controls (one-way ANOVA, Sidak, p = 0.0172).
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Ferroptosis inhibition protects against α-synuclein-related neuronal cell death.
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