Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer's disease retina.

Nat Commun · 2026 · PMC12827417 · PMID 41571675

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a nonsignificant trendno p-value reported

Quantitative IHC analysis revealed significant 2.2- and 3.0-fold increases in retinal NGSDMD and CCasp3 signals, respectively, in AD versus normal-cognition controls ( p < 0.001–0.0001), whereas MCI retinas exhibited a nonsignificant trend toward elevation (Fig. 4G , I).

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