Barely Significant
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The efficacy and safety of tislelizumab combined with weekly nab-paclitaxel, carboplatin, and cetuximab as first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma: a real-world study.

Front Immunol · 2025 · PMC12827551 · PMID 41583496

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hedged sentence
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closest p · 2.0× alpha
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boldest claim

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a trend toward significanceP < 0.1so close (0.05 < p ≤ 0.1)
First, univariate Cox regression identified three variables with a trend toward significance for PFS (P < 0.1): BMI, HALP, and SII; and three variables for OS (P < 0.05): location, HALP, and post-treatment SII changes.

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