A few years later, a systematic review of AD patient studies concluded that plasma levels of vitamins A (9 studies, I 2 = 87%), C (8 studies, I 2 = 88%), E (20 studies, I 2 = 87%), B 12 (37 studies, I 2 = 87%), and folate (31 studies, I 2 = 88%) were significantly lower in patients with AD but vitamin D (5 studies, I 2 = 95%) did not achieve significance ( 127 ).
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Linking dietary patterns to Alzheimer's disease biomarkers with network mathematical modeling could enable new approach methodologies in preventative AD research: a narrative interdisciplinary review.
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The sentences
This is a challenging and long-term endeavor but the benefits may be significant.