highly significantP < 0.01
The mean differences were considered significant for * P < 0.05, and highly significant for ** P < 0.01, *** P < 0.001, or **** P < 0.0001.
The mean differences were considered significant for * P < 0.05, and highly significant for ** P < 0.01, *** P < 0.001, or **** P < 0.0001.