Barely Significant
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Metformin Sensitizes PTEN-deficient Prostate Cancer to PARP Inhibitors by Rebuilding NADP<sup>+</sup> Homeostasis.

Int J Biol Sci · 2026 · PMC12837654 · PMID 41608616

Europe PMCDOI
1
hedged sentence
0.0110
closest p · 0.2× alpha
0.0110
boldest claim

The sentences

a nonsignificant trendp = 0.011actually significant
PTEN mutation combined with Met treatment significantly improved PFS (p = 0.0017) and demonstrated a nonsignificant trend for OS improvement (p = 0.011) (Figures 1 D, E).

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