Energy-Dense High-Fat/High-Sucrose Diet to Induce Type 2 Diabetes Mellitus in BALB/c Mice Without Genetic Modifications and Chemical Agents.

Although the increase in visceral fat in HCD-fed BALB/c mice was not as significant as in HCD-fed C57BL/6 mice, the high triglyceride levels in HCD-fed BALB/c mice and the hypertrophy observed in adipocytes, which indicates adipose tissue dysfunction, suggest that HCD-fed BALB/c mice can accumulate visceral fat despite not gaining weight.

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