Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives.

Int J Mol Sci · 2026 · PMC12841019 · PMID 41596342

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highly significantno p-value reported

(2020) analyzed over 100,000 Israeli men tested between 2006 and 2019 and reported a highly significant age-independent drop in total T across all adult age groups [ 13 ].

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