Neuronal injury biomarkers GFAP and neurofilament light chains (NfL) are associated with neurotoxicity and endothelial dysfunction in adult patients treated with antiCD19 CART cells.

Clin Exp Med · 2026 · PMC12847193 · PMID 41553539

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a trend toward significanceno p-value reported

We also identified a correlation between baseline NfL levels, worse ECOG, and biological markers of endothelial inflammation, as assessed by the mEASIX score and LDH, with a trend toward significance also observed for CRP.

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