Lysosomal exocytosis by macrophages as a druggable mechanism for anti-inflammatory clearance of dead adipocytes in adipose tissue.

Cell Death Dis · 2025 · PMC12848297 · PMID 41436477

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highly significantno p-value reported

Bulk RNA sequencing of ATMs revealed a highly significant impact of Rapamyin on ATM proliferation.

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a slight trendno p-value reported

Marker genes for M1, M2, and Mme macrophages were inconsistently regulated, whereas there is a slight trend toward upregulation of lysosomal genes (Supplementary Fig. 3C, D ).

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