Transnasal humidified rapid insufflation ventilatory exchange versus conventional facemask breathing for preoxygenation during anesthesia induction in TBI surgery: a randomized controlled trial.

With the prolongation of time, rScO2 of the operative and non-operative sides in the conventional mask ventilation group showed a decreasing trend after reaching the peak value at 10 min of preoxygenation; while rScO2 of the operative and non-operative sides in the THRIVE group continued to increase, and the rScO2 of the operative and non-operative sides were significantly higher than that of the conventional mask ventilation group at the 10 min of preoxygenation and the immediate moment of successful intubation (Fig. 2 .A and B).

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