CYP4X1/sEH-Dependent Endocannabinoid Metabolism Drives Fibroblast-Mediated Immunosuppression to Limit Immunotherapy in Colon Cancer.

Adv Sci (Weinh) · 2026 · PMC12849875 · PMID 41276938

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an increasing trendno p-value reported

nucleatum provoked an increasing trend in CYP4X1 expression and a repression in EPHX2 expression ( GSE141805 ), suggesting that CYP4X1 and EPHX2 may be regulated by F. nucleatum .

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