Efficacy and safety of over-the-scope endoscopic suturing device for closure of defects after endoscopic submucosal dissection: a systematic review and meta-analysis.

7 , 26 Use of OSS seems to be an overall effective and safe method for full-thickness closure of defects after ESD with an overall trend toward shorter intervention time as users become more familiar with the device. 7 However, the downsides to use of OSS include limited maneuverability, cumbersome operation, and possible equipment malfunction while in use.

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