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Endothelial MLKL Inhibition Reduces Hyperoxia-Induced Bronchopulmonary Dysplasia in Neonatal Mice.

J Cell Mol Med · 2026 · PMC12853218 · PMID 41608843

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an increasing trendno p-value reported
Although advancements in oxygen therapy have notably increased the overall survival of these infants, the prevalence of BPD has not shown a corresponding decline; instead, it has shown an increasing trend [ 33 ].

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a decreasing trendno p-value reported
Quantitative analysis of Masson‐stained lung sections further showed that, under hyperoxic conditions, the fibrotic area in MLKL iΔEC/ΔEC mice exhibited a decreasing trend compared with hyperoxic MLKL loxP/loxP mice (Figure 4H,I ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.