Development and validation of a two-stage machine learning model for personalised type 2 diabetes screening in the All of Us Research Program and UK Biobank.

BMJ Open · 2026 · PMC12853511 · PMID 41592831

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp=2.3×10−23actually significant

Differences across quartiles were highly significant (global χ 2 p=2.3×10−23), reflecting clear enrichment of PRS benefit in individuals with greater genetic predisposition.

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