Treatment Pathway and Clinical Outcomes of the Population with Muscle-invasive Bladder Cancer in Italy: A Real-world Analysis with Administrative Databases.

Adv Ther · 2026 · PMC12858591 · PMID 41317236

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The above-mentioned RWE Dutch study reached similar results, with only 9% of patients with MIBC enrolled between 2008 and 2016 receiving a neoadjuvant chemotherapy: despite an increasing trend in the use of cisplatin-based chemotherapy regimens, a significant proportion of patients did not receive guideline-recommended chemotherapy, potentially because of factors such as age, comorbidities, and performance status [ 20 , 35 ].

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