Barely Significant
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Paradoxical G-quadruplex distribution in coronavirus genomes reveals functional constraints and antiviral therapeutic opportunities.

Virus Res · 2026 · PMC12860367 · PMID 41570921

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highly significantno p-value reported
G-content adjusted IRRs remained highly significant (Spike: 19.4; Nucleocapsid: 13.7), demonstrating that regional enrichment cannot be explained by nucleotide composition alone. 3.5.

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