Directed evolution of phage Romulus in biofilm-embedded <i>Staphylococcus aureus</i>: mutations in baseplate proteins enhanced its antibiofilm activity.

Biofilm · 2026 · PMC12860735 · PMID 41631269

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highly significantno p-value reported

Based on bioinformatic analysis, gp54 matched to nine highly significant sequences (E-value ≈ 0), indicating a likely biological functional closeness ( Table S3 ).

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Directed evolution of phage Romulus in biofilm-embedded &lt;i&gt;Staphylococcus aureus&lt;/i&gt;: mutations in baseplate proteins enhanced its antibiofilm activity.

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Directed evolution of phage Romulus in biofilm-embedded <i>Staphylococcus aureus</i>: mutations in baseplate proteins enhanced its antibiofilm activity.