39 In addition, the mean duration of oral endocrine drug use in this study was 25 months (> 2 years), and with a longer period of oral endocrine drug use, medication adherence showed a decreasing trend. 40 Symptom distress is negatively correlated with medication adherence Our findings confirmed the negative correlation between symptom distress and medication adherence ( r = −0.663, P < 0.01).
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The effect of symptom distress on medication adherence in patients with breast cancer undergoing endocrine therapy: A moderated mediation model.
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