A marginally significant interaction between APOE 4 status and estradiol was also observed (0.09 [−0.003, 0.19], p for interaction = 0.06), with a positive association between estradiol and 27HC only for APOE 4 carriers (0.13 [0.02, 0.24], P = 0.02).
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Exploring biomarkers of neurodegenerative risk: associations of oxysterols, sex hormones, and reproductive characteristics in older women.
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