MHC in newts illuminates the evolutionary dynamics of complex regions in giant genomes.

Genome Res · 2026 · PMC12863176 · PMID 41526191

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closest p · 0.0× alpha

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boldest claim

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highly significantP -values < 0.001actually significant

There was evidence of selection relaxation for MHC-I-like1: a highly significant ( P -values < 0.001) RELAX test result for the branch leading to MHC-I-like1 cluster (k: 0.356, LRT: 401.7), and for the cluster itself (k: 0.476, LRT: 42.7), as compared to the MHC-I sequences.

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