an increasing trendP < 0.001
Acidosis In the 6-month study, the number (%) of patients who newly initiated or increased sodium bicarbonate was 1 (0.70%) at baseline, 6 (4.58%) at month 3, and 13 (10.16%) at month 6, showing an increasing trend (GLMM analysis: β = 2.070, P < 0.001).