Elevated serotonin receptor 2A signaling restores learning and memory in a Fragile X syndrome model.

Sci Rep · 2026 · PMC12864886 · PMID 41501339

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closest p · 0.0× alpha

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boldest claim

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highly significantp = 1.477 × 10 –8actually significant

Compared to the dfmr1 mutants, the Trhn overexpression results in a highly significant elevation of serotonin in the MB ( UH1 -Gal4 driven Trhn overexpression; p = 1.477 × 10 –8 ), with a similar elevation from the other drivers (Fig. 2 D, right).

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