Shear Stress Initiates Endothelial-to-Mesenchymal Transition in Endocardial Endothelial Cells.

Ann Biomed Eng · 2026 · PMC12866971 · PMID 41606256

Europe PMC DOI

hedged sentence

0.0569

closest p · 1.1× alpha

0.0569

boldest claim

The sentences

a slight trendp = 0.0569so close (0.05 < p ≤ 0.1)

The inflammatory marker, ICAM1, was upregulated at 1.5 hours in response to increased shear (26–38% increase; p = 0.0006-0.0096 for M and H) but did not demonstrate differences at later time points, other than a slight trend of a reduction with shear at 8 hours (15% decrease; p = 0.0569).

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