Dynamic heterogeneity towards drug resistance in AML cells is primarily driven by epigenomic mechanism unveiled by multi-omics analysis.

J Adv Res · 2026 · PMC12869214 · PMID 40409464

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an increasing trendno p-value reported

CytoTRACE analysis, which assesses transcriptional diversity to predict differentiation states and stemness [ 38 ], showed an increasing trend in developmental potential with prolonged Ara-C treatment.

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