Premenopausal serum midkine levels and risk of estrogen receptor positive breast cancer: a prospective, nested case-control study.

Breast Cancer Res · 2026 · PMC12870286 · PMID 41495788

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marginally significantno p-value reported

In this nested case–control study within the NYUWHS, we observed a marginally significant inverse association between serum midkine levels and breast cancer risk.

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marginally statistically significantno p-value reported

Results Higher circulating midkine levels were associated with a marginally statistically significant lower risk of ER + breast cancer.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.