Implementation outcomes of a symptom management intervention in ambulatory oncology practices evaluated using a cluster randomized stepped-wedge trial design.

Implement Sci · 2025 · PMC12870884 · PMID 41331816

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.1000

boldest claim

The sentences

marginally significantp = 0.053so close (0.05 < p ≤ 0.1)

The weighted model, however, indicated a small, marginally significant negative effect (mean difference −0.01 (per 100 patients) CI: −0.01 to 0.00, p = 0.053), suggesting that larger clinics might have had slightly lower reach in the weighted model (adjusting rates for clinic size).

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did not quite reach significancep = 0.10so close (0.05 < p ≤ 0.1)

In the primary model, the effect on the reach of alerts was positive compared to the pre-implementation period but did not quite reach significance (mean difference = 0.08, CI: −0.01 to 0.18, p = 0.10,), with a risk ratio of 1.66 (CI: 0.79 to 3.48).

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