highly significantp < 0.001
4 F) showed that 15 key genes exhibited highly significant differences between subtype A (Cluster1) and subtype B (Cluster2) ( p < 0.001), namely CHEK1 , BRCA1 , CLSPN , CCNB1 , CCNA2 , TRAP1 , RAN , UCHL1 , LMNB1 , UBE2N , PSMA5 , FLNA , KDM1B , NPM1 , and NUMA1 .