GLP-2 alleviates postmenopausal osteoporosis by acting on osteoblasts through the PI3K/AKT/FOXO1 signalling pathway to downregulate FGF23 expression.

J Orthop Surg Res · 2026 · PMC12874791 · PMID 41572358

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a nonsignificant trendno p-value reported

Compared with those in the sham group, the BV/TV and Tb.N in the OVX group significantly decreased, the Tb.Sp and Tb.Pf values in the OVX group increased, and the Tb.Th in the OVX group showed only a nonsignificant trend.

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