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Anti-angiogenic therapies in cancer: from endogenous inhibitors to bispecific VEGF x PD-(L)1 antibodies.

Front Immunol · 2026 · PMC12876227 · PMID 41659853

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a positive trendno p-value reported
The first global Phase 3 trial to evaluate ivonescimab plus chemotherapy (HARMONi) ( NCT06396065 ) in a post-EGFR TKI NSCLC setting showed an increase in PFS consistent with the HARMONi-A study and a positive trend in OS.

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