A first study concentrating on follow-up of MCI patients converting to AD showed no significant differences in Aß plasma levels ( 10 ), while in one of the largest MCI follow-up studies ( 11 ) in which also early dementia cases were included, highly significant reductions in the plasma Aß42/Aß40 ratio and in Aß42 levels were reported.
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Evolution of Abeta42 and Abeta40 levels and Abeta42/Abeta40 ratio in plasma during progression of Alzheimer's disease: a multicenter assessment.
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