Population Pharmacokinetics of Levosimendan and its Metabolites OR-1855 and OR-1896 in Critically Ill Adults, Neonates and Infants on Veno-Arterial ECMO.

OR-1855 concentrations from the neonate were excluded from the popPK analysis, as they showed a decreasing trend throughout the investigation period, likely due to residual concentrations from the first infusion (Fig. 1 , dashed lines), which could unfortunately not be modelled because of the lack of related data.

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