While large registry-based studies have shown modestly significant associations between type 1 diabetes and several autoimmune diseases other than type 1 diabetes in the family, we could not observe such associations, suggesting that even large cohort studies cover too small a population to demonstrate a robust association with rare diseases [ 32 ].
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Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity.
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