MSDC-0160, a novel clinical-stage mitochondrial pyruvate carrier inhibitor, suppresses osteoclast differentiation and alleviates type 2 diabetes-related bone loss.

J Transl Med · 2026 · PMC12882595 · PMID 41519796

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an increasing trendno p-value reported

Quantitative analysis revealed a marked reduction in BV/TV, Tb.N, and Tb.Th, while Tb.Sp exhibited an increasing trend (Fig. 1 B).

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