Barely Significant
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Rapamycin Reverses the Hepatic Response to Diet-Induced Metabolic Stress That Is Amplified by Aging.

Aging Cell · 2026 · PMC12882742 · PMID 41653162

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highly significantno p-value reported
Of 2467 genes upregulated by HFD + veh in hepatocytes of old mice, 72% (1788 genes) were downregulated by HFD + eRapa, a highly significant 6.5‐fold enrichment over random (Figure 3H ).

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