Such divergence reflects an increasing trend in global guideline adaptation, as evidenced by other efforts (e.g., ASH venous thromboembolism guideline for Latin America and the American College of Rheumatology guidelines for rheumatoid arthritis in both the Eastern Mediterranean Region and Saudi Arabia), where panels shifted the balance of benefits and harms based on local infrastructure or reinterpreted the strength of recommendations to reflect target population relevance [ 5 , 63 ].
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Recommendations for Stress Ulcer Prophylaxis in Critically Ill Adults: A Contextualized Clinical Practice Guideline From the Saudi Critical Care Society and the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Endorsed by the Kuwait Anesthesia and Critical Care Society.
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