Quantitative assays clearly showed a highly significant increase in biofilm biomass in the OE strain compared to the WT strain ( Figure 4C ), directly confirming CRP’s crucial regulator role in the biofilm development of KP.
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Overexpression of the <i>crp</i> gene promotes biofilm formation and increases antibiotic resistance in bovine-derived <i>Klebsiella pneumoniae</i>.
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