Role of DNA methylation in regulating inflammatory cytokine expression in neonates with late-onset sepsis.

Front Immunol · 2025 · PMC12883824 · PMID 41668768

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a notable trendno p-value reported

A notable trend of hypomethylation in pro-inflammatory genes (e.g., TLR-2, TLR-4, IL-1β) and hypermethylation in anti-inflammatory genes (e.g., TGF-β, FOXP3) was observed in sepsis groups compared to controls.

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