Effect Modification by Total Bilirubin on the Association Between Hypertension and Cerebral Small Vessel Disease.

J Stroke · 2026 · PMC12883877 · PMID 41478713

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marginally significantno p-value reported

After stratification according to these thresholds, hypertension appeared to be differently associated with CSVD presence between participants with TBIL values below and above these thresholds, with marginally significant P values for effect modification (Wardlaw: P for interaction=0.077; Rothwell: P for interaction=0.053) ( Supplementary Table 10 ).

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