A circulating microRNA-based diagnostic model for breast cancer, in which the miR-139-3p/RPA2 axis regulates the sensitivity to DNA-damaging agents.

Transl Cancer Res · 2026 · PMC12885918 · PMID 41674957

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highly significantno p-value reported

We confirmed this in the BC cell lines and found that the downregulation of CHK1 by miR-139-3p was extremely mild (data not provided), while the downregulation of RPA2 was highly significant.

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