Dual-mode aptamer-driven biosensing platform for ultrasensitive and mutation-resilient detection of the SARS-CoV-2 nucleocapsid protein.

Genes Dis · 2026 · PMC12886537 · PMID 41674662

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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highly significantp < 0.0001actually significant

As shown in Figure 5 C, the results of specificity testing using a double-antibody sandwich ELISA indicated that, compared with the blank control, the assay had a highly significant ability to detect the SARS-CoV-2 N protein ( p < 0.0001).

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marginally significantp < 0.01actually significant

However, InFlu B also produced a marginally significant signal ( p < 0.01), indicating partial cross-reactivity and thus reduced specificity for the SARS-CoV-2 N protein.

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