Barely Significant
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Letter regarding "efficacy of esketamine in reducing nausea and vomiting after anesthesia: a systematic review and meta-analysis of randomized controlled trials".

Ann Med · 2026 · PMC12888357 · PMID 41663054

Europe PMCDOI
1
hedged sentence
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closest p · 1.0× alpha
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boldest claim

The sentences

marginally significantp = 0.05actually significant
The meta-analyses revealed that esketamine was associated with a significant reduction in the risk of nausea (RR = 0.69; 95% CI: 0.50–0.94; p = 0.02; I 2 = 75%) and a marginally significant reduction in vomiting (RR = 0.72; 95% CI: 0.51–1.00; p = 0.05; I 2 = 71%).

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