Optimizing ribociclib dosing in breast cancer with brain metastasis patients using a physiologically based pharmacokinetic model.

BMC Cancer · 2026 · PMC12888661 · PMID 41530705

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an increasing trendno p-value reported

Introduction Breast cancer is the most common malignant tumor among women, with its incidence showing an increasing trend with an annual average growth rate of 0.92% [ 1 ].

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