-in-epmc yes pmc-license-ref CC BY-NC-ND 1 Introduction Transdermal drug delivery systems (TDDS) offer numerous advantages, including consistent and stable plasma levels, avoidance of the first-pass effect in the liver, good patient compliance, and cessation of treatment as needed, all of which are highly significant in medical practice 1 , 2 , 3 .
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Skin-penetrating peptides derived from computational simulation improve transdermal absorption and facilitate topical treatment of melanoma.
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