Xinfeng capsule improves hyperinflammation-associated hypercoagulability and self-perception in osteoarthritis by regulating KLF4 through METTL14-mediated m<sup>6</sup>A modification of lncRNA MEG3.

Front Immunol · 2026 · PMC12894041 · PMID 41694352

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an increasing trendno p-value reported

The results demonstrated that both global m 6 A levels and lncRNA MEG3 m 6 A levels showed an increasing trend in OA patients compared with healthy controls, suggesting the presence of abnormal m6A modification in OA.

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Xinfeng capsule improves hyperinflammation-associated hypercoagulability and self-perception in osteoarthritis by regulating KLF4 through METTL14-mediated m&lt;sup&gt;6&lt;/sup&gt;A modification of lncRNA MEG3.

The sentences

Xinfeng capsule improves hyperinflammation-associated hypercoagulability and self-perception in osteoarthritis by regulating KLF4 through METTL14-mediated m<sup>6</sup>A modification of lncRNA MEG3.